GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs3796352 | 1 | rs71301809 | chr3:53090312 | RFT1 | chr3:53122503-53164470:- | 0.64 | 7.59 | 1.65E-13 | Immune reponse to smallpox (secreted IL-2) |
| THCA | cis | rs3796352 | 1 | rs71301809 | chr3:53090312 | TMEM110 | chr3:52867139-52931547:- | 0.32 | 3.77 | 0.000184 | Immune reponse to smallpox (secreted IL-2) |
| THCA | cis | rs3796352 | 1 | rs71301814 | chr3:53117663 | RFT1 | chr3:53122503-53164470:- | 0.63 | 7.39 | 6.57E-13 | Immune reponse to smallpox (secreted IL-2) |
| THCA | cis | rs3796352 | 1 | rs71301814 | chr3:53117663 | SFMBT1 | chr3:52938628-53080070:- | -0.2 | -3.41 | 0.000717 | Immune reponse to smallpox (secreted IL-2) |
| THCA | cis | rs3829251 | 1 | rs7130829 | chr11:71237702 | NADSYN1 | chr11:71164217-71212579:+ | 0.17 | 3.89 | 0.000114 | Vitamin D levels |
| THCA | cis | rs1834481 | 1 | rs7131094 | chr11:112044917 | BCO2 | chr11:112046208-112095421:+ | 0.24 | 4.89 | 1.37E-6 | Interleukin-18 levels |
| THCA | cis | rs1834481 | 1 | rs7131094 | chr11:112044917 | IL18 | chr11:112013976-112034840:- | -0.23 | -4.36 | 1.62E-5 | Interleukin-18 levels |
| THCA | cis | rs13315871 | 1 | rs71311855 | chr3:58320507 | PXK | chr3:58318617-58410878:+ | 0.33 | 5.99 | 4.22E-9 | Cholesterol, total |
| THCA | cis | rs13315871 | 1 | rs71311857 | chr3:58323377 | PXK | chr3:58318617-58410878:+ | 0.34 | 6.03 | 3.22E-9 | Cholesterol, total |
| THCA | cis | rs13315871 | 1 | rs71311858 | chr3:58323793 | PXK | chr3:58318617-58410878:+ | 0.34 | 6.03 | 3.22E-9 | Cholesterol, total |
| THCA | cis | rs13315871 | 1 | rs71311864 | chr3:58372324 | PXK | chr3:58318617-58410878:+ | 0.34 | 6.01 | 3.64E-9 | Cholesterol, total |
| THCA | cis | rs13315871 | 1 | rs71311865 | chr3:58372423 | PXK | chr3:58318617-58410878:+ | 0.34 | 6.01 | 3.64E-9 | Cholesterol, total |
| THCA | cis | rs13315871 | 1 | rs71311868 | chr3:58392874 | PXK | chr3:58318617-58410878:+ | 0.33 | 5.81 | 1.16E-8 | Cholesterol, total |
| THCA | cis | rs13315871 | 1 | rs71311869 | chr3:58398922 | PXK | chr3:58318617-58410878:+ | 0.33 | 5.77 | 1.42E-8 | Cholesterol, total |
| THCA | cis | rs13315871 | 1 | rs71311870 | chr3:58399283 | PXK | chr3:58318617-58410878:+ | 0.33 | 5.77 | 1.42E-8 | Cholesterol, total |